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KMID : 1036720170500060595
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Journal of Nutrition and Health
2017 Volume.50 No. 6 p.595 ~ p.602
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The impact of malnutrition on survival in patients with gynecologic cancer undergoing chemotherapy
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Nho Ju-Hee
Kwon Yong-Soon
Jo Seong-Il
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Abstract
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Purpose: Malnutrition is a major concern in patients with gynecologic cancer receiving chemotherapy. The aim of this study was to evaluate the prognostic significance of malnutrition in patients with gynecologic cancer undergoing chemotherapy.
Methods: A prospective, observational study was conducted on a total of 99 subjects who were treated at a tertiary hospital in Korea. Data regarding demographic, clinical, nutritional, and psychological characteristics at baseline and survival were obtained.
Results: Performance status, nutritional status, depression, and annual income were significantly different between survivors and non-survivors. Multivariate Cox modeling after adjusting for other factors showed that a malnourished status in patients with gynecologic cancer undergoing chemotherapy was a significant and independent negative influencing factor for survival.
Conclusion: These findings provide evidence that adequate nutritional assessment and intervention may assist in improving survival in patients with gynecologic cancer undergoing chemotherapy.
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KEYWORD
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gynecologic neoplasm, malnutrition, survival, chemotherapy
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